TECHNOLOGY
IntelliPulse™ — cellular
delivery of therapeutics
Reversible electroporation uses short electrical pulses to briefly open the cell membrane, allowing virtually any therapeutic to enter the cell — the most direct, accurate and effective methodology of therapeutic delivery. Once the pulse stops, the cell closes, trapping the therapeutic inside the targeted cells.
What is reversible electroporation?
01
Before Pulse
The cell membrane is intact. Therapeutic molecules remain outside the cell and cannot cross.
02
During E-Field
The electric field induces a voltage across the cell membrane, transiently opening pores and introducing genes or drugs.
03
After Pulse
The membrane reseals and the cell heals with the gene or drug now inside.
Enhanced molecular delivery
Moderate heat (43°C), real-time impedance feedback, and addressable electrodes assure the practitioner that delivery has occurred — and make over-treatment impossible.
How does IntelliPulse™ work?
Drug Delivery
Chemotherapy is driven into tumor cells, causing cell death via the drug’s own mechanism of action at a fraction of systemic dose.
Gene Delivery
Cells take up a gene and then produce the therapeutic molecule it encodes, turning the tumor into its own drug factory.
Ablation
Over-pulsation is used to directly kill cells via irreversible electroporation, without thermal damage to surrounding structures.
Competitive advantage
150V
vs. 1300V legacy systems
Dramatically lower voltage than incumbent electroporation platforms.
Real-Time
Impedance feedback
Tumor Sense reads tissue during treatment and adapts delivery.
1/10th
Procedure cost
Roughly one tenth the cost of a comparable radiotherapy course.
Market overview
Other electroporation systems in clinical use today, for context.
Human market
- IGEA — Europe only, costly, older-generation technology, palliative care indications.
- AngioDynamics — US-based, ablation only.
Veterinary market
- Leroy Biotech — Europe-based alternative.
- OnkoDisruptor — Europe-based alternative.
- VetiQure — Europe-based alternative.
- Clinivet — Europe-based alternative.